RNase-Free Water
2025-10-27
RNase-Free Water
2025-10-27
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Semaglutide (API)

Manual

Product Number: RPJ05

Shipping and Storage

Store at -15°C or below, away from light and sealed.

Component

ComponentRPJ05-10gRPJ05-100gRPJ05-500g
Semaglutide (API)10g100g500g

Description

Semaglutide (CAS 910463-68-2) is a glucagon-like peptide-1 (GLP-1) analog produced through biotechnological fermentation using genetic recombinant technology. It stimulates insulin secretion in a glucose-dependent manner by activating GLP-1 receptors, and is used for blood glucose control in adult patients with type 2 diabetes. The long-acting mechanism of semaglutide is based on structural modifications, where an 18-carbon fatty acid side chain is attached to the 26th lysine residue of the peptide. This modification increases the molecular weight of semaglutide and enhances its affinity for albumin by 5-6 times, thereby preventing rapid renal clearance and metabolic degradation, thereby extending its half-life in the body.

Application

  1. Inhibiting glycolysis in tumor cells during cell culture to disrupt tumor growth signaling pathways
  2. Treatment of Type 1 diabetes
  3. Weight management
  4. Non-alcoholic fatty liver disease (NAFLD), neurological disorders

Feature

  1. Produced using biotechnology, the quality is equivalent to that of the original research product.
  2. Compliant with GMP standards.
  3. Complete quality documents: Relevant regulatory support documents can be provided according to customer requirements.

Specification

ProjectFeature
AppearanceWhite or off white powder
Content95.0%~105.0%
Endotoxin<10 EU/mg
Host protein residueNMT 10ng/mg
Exogenous DNA residueNMT 10ng/dose
Polymer proteinNMT 0.3%
Purity≥98.0%

Note

  1. This product should not be stored in high-temperature environments for long periods. 
  2. Contamination should be avoided during the use of this product.

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