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	<title>RPJ05 &#8211; Tinzyme</title>
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		<title>Semaglutide (API)</title>
		<link>https://www.tinzyme.com/recombinant-protein/semaglutide-api/</link>
		
		<dc:creator><![CDATA[tinzyme]]></dc:creator>
		<pubDate>Mon, 27 Oct 2025 09:51:07 +0000</pubDate>
				<category><![CDATA[Recombinant protein]]></category>
		<category><![CDATA[RPJ05]]></category>
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					<description><![CDATA[RPJ05, Semaglutide (API).
Semaglutide (CAS 910463-...]]></description>
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<p><a href="https://www.tinzyme.com/man/RPJ05.pdf" target="_blank" rel="noreferrer noopener">Manual</a></p>



<p><strong>Product Number: RPJ05</strong></p>



<p><strong>Shipping and Storage</strong></p>



<p>Store at -15°C or below, away from light and sealed.</p>



<p><strong>Component</strong></p>



<figure class="wp-block-table"><table class="has-fixed-layout"><tbody><tr><td>Component<strong></strong></td><td>RPJ05-10g</td><td>RPJ05-100g</td><td>RPJ05-500g</td></tr><tr><td>Semaglutide (API)</td><td>10g</td><td>100g</td><td>500g</td></tr></tbody></table></figure>



<p><strong>Description</strong></p>



<p>Semaglutide (CAS 910463-68-2) is a glucagon-like peptide-1 (GLP-1) analog produced through biotechnological fermentation using genetic recombinant technology. It stimulates insulin secretion in a glucose-dependent manner by activating GLP-1 receptors, and is used for blood glucose control in adult patients with type 2 diabetes. The long-acting mechanism of semaglutide is based on structural modifications, where an 18-carbon fatty acid side chain is attached to the 26th lysine residue of the peptide. This modification increases the molecular weight of semaglutide and enhances its affinity for albumin by 5-6 times, thereby preventing rapid renal clearance and metabolic degradation, thereby extending its half-life in the body.</p>



<p><strong>Application</strong></p>



<ol class="wp-block-list">
<li>Inhibiting glycolysis in tumor cells during cell culture to disrupt tumor growth signaling pathways</li>



<li>Treatment of Type 1 diabetes</li>



<li>Weight management</li>



<li>Non-alcoholic fatty liver disease (NAFLD), neurological disorders</li>
</ol>



<p><strong>Feature</strong></p>



<ol class="wp-block-list">
<li>Produced using biotechnology, the quality is equivalent to that of the original research product.</li>



<li>Compliant with GMP standards.</li>



<li>Complete quality documents: Relevant regulatory support documents can be provided according to customer requirements.</li>
</ol>



<p><strong>Specification</strong></p>



<figure class="wp-block-table"><table class="has-fixed-layout"><tbody><tr><td>Project<strong></strong></td><td>Feature</td></tr><tr><td>Appearance</td><td>White or off white powder</td></tr><tr><td>Content</td><td>95.0%~105.0%</td></tr><tr><td>Endotoxin</td><td>&lt;10 EU/mg</td></tr><tr><td>Host protein residue</td><td>NMT 10ng/mg</td></tr><tr><td>Exogenous DNA residue</td><td>NMT 10ng/dose</td></tr><tr><td>Polymer protein</td><td>NMT 0.3%</td></tr><tr><td>Purity</td><td>≥98.0%</td></tr></tbody></table></figure>



<p><strong>Note</strong></p>



<ol class="wp-block-list">
<li>This product should not be stored in high-temperature environments for long periods. </li>



<li>Contamination should be avoided during the use of this product.</li>
</ol>



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<h4 class="wp-block-heading"><strong>Get a quote now</strong></h4>



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