This product is a GMP grade recombinant deoxyribonuclease I (DNase I), which can randomly decompose single or double stranded DNA to produce 5′- p-terminal oligonucleotides. DNase I can cut double stranded DNA at will under Mg2+; Under Mn2+ condition, DNase I can cut DNA double strand at the same site to form flat end or stick end with 1-2 nucleotides protruding.

This product is a large-scale expression of recombinant DNase I in E. coli, with a molecular weight of about 39kD, which conforms to GMP production and quality management specifications. All raw and auxiliary materials are traceable.

Specification

• Heavy metal: ≤ 10ppm
• No virus, mycoplasma and other common pathogens
• Internal toxicity control: ≤ 10 EU / mg
• Volume activity(containing cCMP / RNase A): ≥ 40 Ku / ml
• Host protein residue: ≤ 50 ppm
• No RNase activity, cleavage activity
• Host DNA residue: ≤ 100 pg / mg
• There was no nonspecific nuclease activity

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